The Synthesis of 3‐Amino‐pyrazine‐2‐carbohydrazide and 3‐Amino‐N′‐methylpyrazine‐2‐carbohydrazide Derivatives |
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| Authors: | Barbara Milczarska Katarzyna Gobis Henryk Foks Lukasz Golunski Pawel Sowinski |
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| Institution: | 1. Department of Organic Chemistry, Medical University of Gdansk, , Gdansk, 80‐438 Poland;2. Laboratory of NMR Spectroscopy, Department of Chemistry, Gdansk University of Technology, , Gdansk, Poland |
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| Abstract: | In research of new biologically active compounds, the reactions of amino‐pyrazin‐2‐hydrazide and methylhydrazide with isothiocyanates, aromatic aldehydes, ketones, CS2, and formic acid were made. New thiosemicarbazides, 1,3,4‐thiadiazoles, 1,3,4‐oxadiazoles, and 1,2,4‐triazoles were obtained. New 4‐oxopteridine derivative 26 was also synthesized. |
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