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Aluminum phosphate [AlPO4(H)]: A mild and efficient recyclable catalyst for one‐pot synthesis of polyhydroquinoline via the Hantzsch reaction under solvent‐free conditions |
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| Authors: | K Purandhar V Jyothi P Pratap Reddy M Adharvana Chari K Mukkanti |
| Institution: | 1. Research and Development, Matrix Laboratories Limited, Anrich Industrial Estate, Medak District‐502325, A.P., India;2. Research and Development, Macleods Pharmaceuticals Ltd., Shanthi Nagar, Andheri (E), Mumbai‐400 093, Maharashtra, India;3. International Center for Materials Nanoarchitectonics (MANA), National Institute of Material Science, Tsukuba, Japan;4. Department of Chemistry, JNTUH, Kukatpally, Hyderabad‐500072, A.P., India |
| Abstract: | Polyhydroquinolines have been synthesized in good to excellent yields (80–90%) and short reaction times (15–30 min) in the presence of aluminum phosphate AlPO4] as heterogeneous catalyst at 90°C; the reaction workup is simple and the catalyst aluminum phosphate AlPO4] can be easily separated from the product and reused. J. Heterocyclic Chem., (2012). |
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