4-Hydroxy-2-quinolones 143. Synthesis,structure, and spectroscopic characteristics of ethyl 2-hydroxy-4-oxo-4H-pyrazino[1,2-<Emphasis Type="Italic">a</Emphasis>]pyrimidine-3-carboxylate |
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| Authors: | I V Ukrainets I A Tugaibei A A Tkach V B Rybakov A V Turov |
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| Institution: | (1) National University of Pharmacy, Kharkiv, 61002, Ukraine;(2) Kharkiv Medicinal Academy of Postgraduate Education, Kharkiv, 61176, Ukraine;(3) M. V. Lomonosov Moscow State University, Moscow, 119899, Russia;(4) Taras Shevchenko National University, Kiev, 01033, Ukraine |
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| Abstract: | Condensation of aminopyrazine with triethyl methanetricarboxylate gave ethyl 2-hydroxy-4-oxo-4H-pyrazino1,2-a]pyrimidine-3-carboxylate.
According to X-ray analytical data the compound exists in the 2-hydroxy-4-oxo form in the crystal.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 411–419, March, 2008. |
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| Keywords: | aminopyrazine 3-ethoxycarbonyl-2-hydroxy-4-oxo-4H-pyrazino[1 2-a]pyrimidine tris-(ethoxycarbonyl)methane X-ray analysis |
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