| 高效液相色谱法测定皮炎宁酊中间苯二酚和水杨酸的含量 |
| |
| 引用本文： | 郭兴杰,周密.高效液相色谱法测定皮炎宁酊中间苯二酚和水杨酸的含量[J].色谱,1998,16(6):532-533. |
| |
| 作者姓名： | 郭兴杰 周密 |
| |
| 作者单位： | 沈阳药科大学分析教研室 |
| |
| 摘 要： | 采用高效液相色谱法测定了皮炎宁酊中间苯二酚和水杨酸的含量。色谱柱为ＨｙｐｅｒｓｉｌＯＤＳ柱，流动相为Ｖ（甲醇）∶Ｖ（水）∶Ｖ（乙酸）＝５０∶５０∶０．９。检测波长为２８５ｎｍ。在此条件下，间苯二酚和水杨酸可与其降解产物及杂质完全分开。
|
| 关 键 词： | 高效液相色谱法 间苯二酚 皮炎宁酊剂 水杨酸 |
Determination of Resorcinol and Salicylic Acid in Piyanning Tincture by High Performance Liquid Chromatography |
| |
| Guo Xingjie and Zhou Mi.Determination of Resorcinol and Salicylic Acid in Piyanning Tincture by High Performance Liquid Chromatography[J].Chinese Journal of Chromatography,1998,16(6):532-533. |
| |
| Authors: | Guo Xingjie and Zhou Mi |
| |
| Institution: | Shenyang Pharmaceutical University, Shenyang, 110015. |
| |
| Abstract: | A method for the simultaneous determination of resorcinol and salicylic acid in Piyanning tincture by HPLC has been proposed. Operating conditions were Hyppersil ODS column, 4.6 mm x 200 mm, V (methanol): V(water): V(acetic acid) = 50:50:0.9 mobile phase and UV detection at 285 nm. The linear ranges of the method were 0.05-0.25 g/L(r = 1.000) for resorcinol and 0.025-0.127 g/L(r = 1.000) for salicylic acid. The limits of detection were both 0.2 mg/L at a signal-to-noise of 3. The assay method was capable to resolve resorcinol and salicylic acid from their impurities. |
| |
| Keywords: | high performance liquid chromatography Piyanning tincture resorcinol salicylic acid |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《色谱》浏览原始摘要信息 |
| 点击此处可从《色谱》下载免费的PDF全文 |
