Metallo-Phosphorylation of Alkynes: Reaction of Alkynes with Cp2Zr(1-butene) ( PR3 ) and Chlorophosphate

Phosphorylation of alkynes is an attractive reaction for the synthesis of stereodefined alkenylphosphonates that are useful intermediates in organic synthesis. Particularly interesting and challenging reactions are those involving the region- and stereo-selective simultaneous introductions of phosphate and other functional groups to multiple carbon-carbon bonds.[1,2]