Synthesis of cis- and trans-2,5-disubstituted tetrahydrofurans by a tandem dihydroxylation-SN2 cyclization sequence |
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| Authors: | Marshall James A Sabatini Jesse J |
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| Affiliation: | Department of Chemistry, University of Virginia, Charlottesville, 22904, USA. jam5x@virginia.edu |
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| Abstract: | [reaction: see text] Dihydroxylation of delta- and epsilon-mesyloxy alpha,beta-unsaturated esters proceeds with in situ cyclization to afford 2,5-disubstituted and 2,3,5-trisubstituted tetrahydrofurans. |
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