The structure of karakoline

Summary We have isolated from the tubers ofAconitum karakolicum collected in the Kirghiz SSR, Kungei Alatau range, songorine, napelline, a base with mp 159–160°C, and the new alkaloids karakoline and a base with mp 222–224°C.The results of a study of the chemical reactions and spectral characteristics of karakoline have shown that it consists of a lycoctonine skeleton with N-ethyl and C₄-methyl groups, hydroxyls at C₁, C₈, and C₁₀ and a methoxy group at C₁₅.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 199–205, March–April, 1973.