Acylation of pyrrolo[1,2-a]pyrazines |
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| Authors: | V I Terenin M A Butkevich A S Ivanov E V Kabanova |
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| Institution: | (1) M. V. Lomonosov Moscow State University, Moscow, 119992, Russia |
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| Abstract: | The acylation of pyrrolo1,2-a]pyrazines with acetic anhydride and the acid chlorides of various carboxylic acids has been
studied. It has been shown that pyrrole1,2-a]pyrazines are selectively acylated at the α-position of the pyrrole ring when
it is free. Products of the condensation of 1-methylsubstituted pyrrolo1,2-a]pyrazines have been obtained for the first time
in the process of acetylation.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, 263–272, February, 2008. |
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| Keywords: | pyrrolo[1 2-a]pyrazines acylation electrophilic substitution |
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