Lewis acid-promoted imine synthesis by the insertion of isocyanides into C-H bonds of electron-rich aromatic compounds |
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Authors: | Tobisu Mamoru Yamaguchi Seiji Chatani Naoto |
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Affiliation: | Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. |
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Abstract: | The Lewis acid-promoted insertion of isocyanides into aromatic C-H bonds is reported. An imine functionality containing an array of N-substituents can be introduced directly into electron-rich aromatics in good yields. |
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