Total synthesis of (-)-okilactomycin |
| |
| Authors: | Smith Amos B Basu Kallol Bosanac Todd |
| |
| Institution: | Department of Chemistry, Laboratory for Research on the Structure of Matter, and Monell Chemical Senses Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. smithab@sas.upenn.edu |
| |
| Abstract: | A highly convergent synthesis of (-)-okilactomycin is described. Key reactions of this synthesis include a strategy-level diastereoselective oxy-Cope rearrangement/oxidation sequence, a Petasis-Ferrier union/rearrangement tactic, and an efficient RCM reaction to construct the 13-membered macrocyclic ring. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
