| Molecularly Imprinted Polymer with Calix[4]arene Derivative for the Recognition of Acetanilide |
| |
| 作者姓名： | 卢春阳 何海成 何锡文 曾宪顺 |
| |
| 作者单位： | [1]StateKeyLaboratoryofFunctionalPolymerMaterialsforAdsorptionandSeparation,DepartmentofChemistry,NankaiUniversity,Tianjin300071,China [2]DepartmentofChemistry,LangfangNormalCollege,Langfang,Hebei065000,China [3]StateKeyLaboratoryofElemento-organicChemistry,NankaiUniversity,Tianjin300071,China |
| |
| 基金项目： | Project supported by the National Natural Science Foundation of China (Nos. 20175009 and 20375017)，the Doctoral Foundation of Education Ministry of China (No. 2002055002) and Tianjin Natural Science Foundation (No. 033603511). |
| |
| 摘 要： | Two molecularly imprinted polymers binding to analgesic acetanilide were prepared using either dual functional monomers of calix4]arene derivative and acrylamide or single monomer acrylamide, respectively. The polymers were ground, sieved and investigated by equilibrium binding experiment to evaluate their recognition properties for the template and other substrates. Scatchard analysis showed that homogeneous recognition sites were formed in the imprinted polymer matrix. Our results demonstrated that the polymer using two functional monomers exhibited better selectivity for the template. This study may open new frontiers for the development and application of imprinted polymers, such as drug separation and purification.
|
| 关 键 词： | 分子印迹聚合物 功能单体 calixarene 乙酰替苯胺 止痛药 丙烯酰胺 |
Molecularly Imprinted Polymer with Calix[4]arene Derivative for the Recognition of Acetanilide |
| |
| LU,Chun-Yanga HE,Hai-Chenga,cHE,Xi-Wen,a,b.Molecularly Imprinted Polymer with Calix[4]arene Derivative for the Recognition of Acetanilide[J].Chinese Journal of Chemistry,2004,22(3):275-278. |
| |
| Authors: | LU Chun-Yanga HE Hai-Chenga cHE Xi-Wen a b |
| |
| Institution: | LU,Chun-Yanga HE,Hai-Chenga,cHE,Xi-Wen*,a,b |
| |
| Abstract: | Two molecularly imprinted polymers binding to analgesic acetanilide were prepared using either dual functional monomers of calix4]arene derivative and acrylamide or single monomer acrylamide, respectively. The polymers were ground, sieved and investigated by equilibrium binding experiment to evaluate their recognition properties for the template and other substrates. Scatchard analysis showed that homogeneous recognition sites were formed in the imprinted polymer matrix. Our results demonstrated that the polymer using two functional monomers exhibited better selectivity for the template. This study may open new frontiers for the development and application of imprinted polymers, such as drug separation and purification. |
| |
| Keywords: | molecularly imprinted polymer (MIP) functional monomer calixarene acetanilide |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
