| 微反应器在合成化学中的应用 |
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| 引用本文： | 何伟 方正 陈克涛 万志东 郭凯. 微反应器在合成化学中的应用[J]. 应用化学, 2013, 30(12): 1375-1385. DOI: 10.3724/SP.J.1095.2013.20617 |
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| 作者姓名： | 何伟 方正 陈克涛 万志东 郭凯 |
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| 作者单位： | (南京工业大学1.药学院；2.食品与轻工学院；3.生物与制药工程学院 南京 210009) |
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| 基金项目： | 国家重点基础研究发展计划(973计划,2012CB725204, 2012CB721104) |
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| 摘 要： | 微反应器在传质、换热方面具有较明显的优势，可以强化混合和精确控温，还可以大大缩短工艺筛选和工艺放大的周期。 本文着重从液相反应、气相反应和气/液反应3个方面对微反应技术在合成中的应用做了较详细的评述，同时也简略介绍了其在光化学和电化学反应中的应用，并概要介绍了微反应技术现阶段存在的问题。
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| 关 键 词： | 微反应器 传热 传质 液相反应 气相反应 气液反应 |
| 收稿时间： | 2012-12-31 |
| 修稿时间： | 2013-05-03 |
Application of Microreactor Technology in Synthetic Chemistry |
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| HE Wei,FANG Zheng,CHEN Ketao,WANG Zhidong,GUO Kai. Application of Microreactor Technology in Synthetic Chemistry[J]. Chinese Journal of Applied Chemistry, 2013, 30(12): 1375-1385. DOI: 10.3724/SP.J.1095.2013.20617 |
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| Authors: | HE Wei FANG Zheng CHEN Ketao WANG Zhidong GUO Kai |
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| Affiliation: | (1.School of Pharmaceutical;2.College of Sciences;3.College of Biotechnology and ;Pharmaceutical Engineering,Nanjing University of Technology,Nanjing 210009,China) |
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| Abstract: | Micro Reactor Technique(MRT), which shows great advantages in heat transfer, mass transfer and mixing, can enhance the mixing process and control the reaction temperature precisely. In addition, it can dramatically shorten the screening period and scale-up process. This review emphasized the application of the microreactor technology in liquid phase reaction, gas phase reaction and gas-liquid phase reaction in detail. Meanwhile, photochemistry and electrochemistry were introduced briefly. We also presented the existing problems in such technique. |
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| Keywords: | microreactor heat transfer mass transfer liquid phase microreaction gas phase microreaction gas-liquid phase microreaction |
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