| Synthesis and Crystal Structure of Palladium(Ⅱ) Complex with 2,2’-Bipyridine-3,3’-dicarboxylic Acid |
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| 作者姓名： | 刘瑕 高恩君 程卯生 孙亚光 |
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| 作者单位： | Laboratory of Coordination Chemistry Shenyang Institute of Chemical Technology Shenyang 110142 China，Laboratory of Coordination Chemistry Shenyang Institute of Chemical Technology Shenyang 110142 China College of Pharmaceutical Engineering Shenyang Pharmaceutical University Shenyang 110015 China，College of Pharmaceutical Engineering Shenyang Pharmaceutical University Shenyang 110015 China，Laboratory of Coordination Chemistry Shenyang Institute of Chemical Technology Shenyang 110142 China |
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| 基金项目： | This project was supported by the Science Foundation of Shenyang Institute of Chemical Technology, National Science Foundation for Post-doctoral and Corporation Post-doctoral Foundation of Liaoning Province |
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| 摘 要： | 1 INTRODUCTION As the first inorganic antitumor complex[1], cis- platin (cis-DDP) possesses prominent therapeutic ef- fect for encephaloma, lung cancer and several kinds of genital system tumors[2]. However, cis-DDP has toxic side-effect to a larger extent. Especially due to its damage to kidney, the dose is strictly limited[3]. Therefore, other Pt(II) complexes including carbon- platin were developed[4]. Pd(II) complex is struc- turally similar to Pt(II) complex, so the antitumor …
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| 关 键 词： | palladium complex 2 2’-bipyridine-3 3’-dicarboxylic acid crystal structure |
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