Applications of Raman-based techniques to on-site and in-vivo analysis |
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| Authors: | Rui Liu Jing-fu Liu Xiao-xia Zhou Gui-bin Jiang Rui Liu |
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| Institution: | State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;Graduate University of the Chinese Academy of Sciences, Beijing 100039, China |
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| Abstract: | Raman-based technologies have proved to be excellent tools for on-site and in-vivo analysis, due to the non-invasive nature of their detection, their capability of providing structure information, their high tolerance to aqueous samples, the ultra-sensitivity of surface-enhanced Raman scattering (SERS) and resonance Raman scattering (RRS), the high spatial resolution of tip-enhanced Raman scattering (TERS), and the ultrashort spectra-acquisition time for coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS).In this review, we highlight the recent success of Raman-based technologies in various applications, including:(1) | on-site surface analysis and chemical-reaction monitoring; | (2) | on-site identification of cultural objects, archeological studies and planetary science; | (3) | in-vivo analysis of cells and microorganisms; | (4) | in-vivo diagnosis inside human and animal bodies; | (5) | in-vivo fast Raman imaging and mapping; | (6) | the study of SERS processes; and, | (7) | assessment of nanomaterial safety. |
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| Keywords: | In-vivo analysis Nanomaterial safety Non-invasive detection On-site analysis Raman imaging Raman scattering Structure information Surface analysis Surface-enhanced Raman scattering Ultra-sensitivity |
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