Synthesis and applications of graphene oxide aerogels in bone tissue regeneration: a review |
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| Authors: | ME Berrio A Oñate A Salas K Fernández MF Meléndrez |
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| Institution: | 1. Department of Materials Engineering (DIMAT), Faculty of Engineering, Universidad de Concepción, 270 Edmundo Larenas St, Box 160-C, Concepción 4070409, Chile;2. Research Group in Advanced Nanocomposites (GINA), Department of Materials Engineering (DIMAT), Faculty of Engineering, Universidad de Concepción, 270 Edmundo Larenas St, Box 160-C, Concepción 4070409, Chile;3. Department of Mechanical Engineering (DIMec), Faculty of Engineering, Universidad Del Bío-Bío, 1202 Collao St, Concepción 4051381, Chile;4. Department of Mechanical Engineering (DIM), Faculty of Engineering, Universidad de Concepción, 219 Edmundo Larenas St, Box 160-C, Concepción 4070409, Chile;5. Biomaterials Laboratory, Department of Chemical Engineering University of Concepción, 4070386 Concepción, Chile;6. Unidad de Desarrollo Tecnológico; 2634 Av. Cordillera, Parque Industrial Coronel, Box 4051, Concepción 4191996, Chile |
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| Abstract: | Development of biocompatible porous supports is a promising strategy in the field of tissue engineering for the repair and regeneration of bone tissues with severe damage. Graphene oxide aerogels (GOAs) are excellent candidates for the manufacture of these systems due to their porosity, ability to imitate bone structure, and mechanical resistance, and according to their surface chemical reactivity, they can facilitate osseointegration, osteogenesis, osteoinduction and osteoconduction. In this review, synthesis of GOAs from the most primary source is described, and recent studies on the use of these functionalized carbonaceous foams as scaffolding for bone tissue regeneration are presented. |
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| Keywords: | Aerogels Graphene oxide aerogels Scaffold Bone tissue regeneration |
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