| 低强度超声对小鼠肝癌H_（22）细胞抑制效应的初步研究 |
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| 引用本文： | 徐静,许川山,夏新蜀,王昕娜,王萍,向君彦.低强度超声对小鼠肝癌H_（22）细胞抑制效应的初步研究[J].四川激光,2009,30(6):69-69. |
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| 作者姓名： | 徐静 许川山 夏新蜀 王昕娜 王萍 向君彦 |
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| 作者单位： | 徐静,许川山,王昕娜,王萍,向君彦(重庆医科大学超声影像学研究所,重庆,400010;重庆医科大学附属第二医院康复理疗中心,重庆,400010);夏新蜀(重庆医科大学附属第一医院康复医学科,重庆,400016) |
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| 基金项目： | 本课题受国家高技术研究发展计划 |
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| 摘 要： | 目的：观察低强度超声对小鼠肝癌H22细胞体外生长的影响。方法：以低强度超声辐照小鼠肝癌H22细胞,采用倒置显微镜观察和MTT法检测观察超声对小鼠肝癌H22细胞的抑制作用。结果：低强度超声波能够显著抑制小鼠肝癌H22细胞的增殖,并且跟辐照时间呈剂量依赖关系。辐照后24h其MTT光吸收值随着超声作用时间的延长而显著降低。结论：低频超声辐照对小鼠肝癌H22细胞体外生长具有明显的抑制作用。
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| 关 键 词： | 低强度超声 细胞抑制 小鼠肝癌H22细胞 |
Inhibition of low-intensity ultrasound radiation on hepatocellular carcinomas cell line H_(22) cells |
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| Institution: | XU Jing,XU Chuan-shan,XIA Xin-shu,Wang Xin-na,WANG Ping,XIANG Jun-yan(1.Institute of Ultrasound Imaging,Chongqing Medical University,Chongqing 400010,China;2.Department of Rehabilitation Medicine,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China;3.Center of Rehabilitation Medical,Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010,China) |
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| Abstract: | Objective：To investigate the inhibition effect of low-intensity ultrasound radiation on hepatocellular carcinomas cell line H22 cells.Methods： The growth inhibitory effect of ultrasound exposure（1.7MHz,1.35W/cm2）on H22 cells was observed using light microscopy and MTT colormetric assay.Results： The absorbance value of MTT significantly decreased at 24h after ultrasound radiation as compared to the control.Conclusion ： Ultrasound radiatiion could obviously inhibit the proliferation of H22 cells. |
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| Keywords: | ultrasound radiation hepatocellular carcinomas inhibition |
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