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Synthesis and Insecticidal Activity of New 4-Hydroxy-2H-1-benzopyran-2-one Derivatives
Authors:Meijing Wang  Feng Chen  Jian Guan  Jing Zhao  Jiufu Zhang  Renhe Zhao
Institution:(1) Department of Chemistry, Northeastern University, Shenyang City, 110004, People’s Republic of China;(2) Jialong Naturelite Pharmaceutical R&D Co., Ltd., Anshan City, Liaoning Province, 114014, People’s Republic of China;(3) Department of Organic Chemistry, Myongji University, Yongin, 449728, South Korea
Abstract:Several stable and storable anticoagulant rodenticides involving both merits of acute and chronic rodenticides have been synthesized (Holbrook et al. in Arch Intern Med 165:1095–1106, 2005; Baglin et al. in Br J Haematol 132:277–285, 2006). The structures of synthesized compounds were confirmed by IR, 1H NMR. The compounds were also evaluated for their anticoagulant and acute biologic activity (Lipton et al., JAMA 252:3004–3005, 3).
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