| 电化学和电化学发光核酸适体传感器 |
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| 引用本文： | 袁涛,刘中原,胡连哲,徐国宝.电化学和电化学发光核酸适体传感器[J].分析化学,2011,39(7):972-977. |
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| 作者姓名： | 袁涛 刘中原 胡连哲 徐国宝 |
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| 作者单位： | 1. 中国科学院长春应用化学研究所电分析化学国家重点实验室,长春,130022;中国科学院研究生院,北京,100039
2. 中国科学院长春应用化学研究所电分析化学国家重点实验室,长春,130022 |
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| 基金项目： | 国家自然科学基金，科技部项目，吉林省科技厅项目 |
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| 摘 要： | 核酸适体具有亲合力强、选择性高、稳定性好、易于修饰等优点,广泛用于对目标物如蛋白质、小分子等的灵敏检测.电化学具有成本低、灵敏度高、仪器小巧等优点.近年来,构建基于核酸适体的电化学传感器,已经成为一个热门的研究领域.本文重点评述了2005年以来核酸适体的电化学传感器的研究进展,并展望其发展前景.
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| 关 键 词： | 核酸适体 电化学 传感器 电化学发光 综述 |
| 收稿时间： | 25 January 2011 |
Electrochemical and Electrochemiluminescent Aptasensors |
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| YUAN Tao,LIU Zhong-Yuan,HU Lian-Zhe,XU Guo-Bao.Electrochemical and Electrochemiluminescent Aptasensors[J].Chinese Journal of Analytical Chemistry,2011,39(7):972-977. |
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| Authors: | YUAN Tao LIU Zhong-Yuan HU Lian-Zhe XU Guo-Bao |
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| Institution: | aState Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;bGraduate University of Chinese Academy of Sciences, Beijing 100039, China |
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| Abstract: | Aptamers have been widely used for the detection of target molecules owing to their chemical stability, easy modification and remarkable specificity and affinity for various target molecules. Electrochemical methods are well known for low cost, high sensitivity and usage of miniature instruments. Recently, the design of electrochemical aptasensors has attracted significant attention in the field of biosensors. This paper mainly reviews the developments of these aptasensors since 2005, and discusses the prospects. |
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| Keywords: | Aptamer Electrochemistry Biosensor Electrochemiluminescence Review |
| 本文献已被 CNKI 万方数据 ScienceDirect 等数据库收录！ |
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