Ionic Liquid Promoted Eco-friendly and Efficient Synthesis of 2,3-Dihydroquinazolin-4(1<Emphasis Type="Italic">H</Emphasis>)-ones |
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Authors: | Minoo Dabiri Peyman Salehi Mostafa Baghbanzadeh |
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Institution: | (1) Department of Chemistry, Faculty of Science, Shahid Beheshti University, Evin, Tehran, Iran;(2) Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, Iran |
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Abstract: | Summary. 2,3-Dihydroquinazolin-4(1H)-ones were efficiently synthesised by the reaction of isatoic anhydride, a primary amine or ammonium acetate, and different
aromatic aldehydes in 1-butyl-3-methylimidazolium tetrafluoroborate (bmim]BF4) without using any acidic catalyst. Also a bis-derivative of the title compound as a polyheterocyclic system was synthesised
successfully in high yield. |
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Keywords: | , 2,3-Dihydroquinazolinone, Heterocycles, Green chemistry, Ionic liquid, |
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