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Ionic Liquid Promoted Eco-friendly and Efficient Synthesis of 2,3-Dihydroquinazolin-4(1<Emphasis Type="Italic">H</Emphasis>)-ones
Authors:Minoo Dabiri  Peyman Salehi  Mostafa Baghbanzadeh
Institution:(1) Department of Chemistry, Faculty of Science, Shahid Beheshti University, Evin, Tehran, Iran;(2) Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, Iran
Abstract:Summary. 2,3-Dihydroquinazolin-4(1H)-ones were efficiently synthesised by the reaction of isatoic anhydride, a primary amine or ammonium acetate, and different aromatic aldehydes in 1-butyl-3-methylimidazolium tetrafluoroborate (bmim]BF4) without using any acidic catalyst. Also a bis-derivative of the title compound as a polyheterocyclic system was synthesised successfully in high yield.
Keywords:, 2,3-Dihydroquinazolinone, Heterocycles, Green chemistry, Ionic liquid,
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