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First total synthesis of Pestalotioprolide C and its C7 epimer
Authors:K Siva Nagi Reddy  Gowravaram Sabitha
Institution:Natural Products Chemistry Division and CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India;Academy of Scientific and Innovative Research (AcSIR), New Delhi 110020, India
Abstract:The first total synthesis of Pestalotioprolide C and C7-epi-Pestalotioprolide C adopting Noyori asymmetric reduction, HWE Olefination and Shiina macrolactonization as the key steps has been described.
Keywords:Pestalotioprolide C  Total synthesis  Noyori asymmetric reduction  HWE olefination  Macrolactonization
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