Patterning of cells on a PVC film surface functionalized by ion irradiation |
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| Authors: | Chan‐Hee Jung In‐Tae Hwang Ho‐Je Kwon Young‐Chang Nho Jae‐Hak Choi |
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| Institution: | Radiation Research Division for Industry and Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup‐si, Jeollabuk‐do 580‐185, Korea |
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| Abstract: | Micropatterns of cells on a poly(vinyl chloride) (PVC) film surface were created by using ion irradiation. A PVC film was irradiated with H+ ions through a pattern mask in order to create patterns of the hydrophilic/hydrophobic regions on the PVC surface. The effect of ion irradiation on the surface properties of the PVC film was characterized by using Fourier transform‐infrared spectroscopy (FT‐IR), water contact angle measurement, and X‐ray photoelectron spectroscopy (XPS). The results revealed that the chemical environment of the PVC film surface was effectively changed by ion irradiation due to dehydrochlorination and oxidation. The in vitro cell culture on the patterned PVC film surface showed selective adhesion and proliferation of the cells on the ion‐irradiated regions. Well‐defined 50 µm patterns of the cells were obtained on the PVC film surface irradiated to 1 × 1015 ions/cm2. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Keywords: | ion irradiation surface modification poly(vinyl chloride) cell patterning |
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