首页 | 本学科首页   官方微博 | 高级检索  
     


Electrospun Fibrous Scaffolds with Multiscale and Photopatterned Porosity
Authors:Harini G. Sundararaghavan  Robert B. Metter  Jason A. Burdick
Affiliation:University of Pennsylvania, Department of Bioengineering, 210 S 33rd Street, Philadelphia, PA 19104, USA
Abstract:The structural and mechanical properties of tissue engineered environments are crucial for successful cellular growth and tissue repair. Electrospinning is gaining wide attention for the fabrication of tissue engineered scaffolds, but the small pore sizes of these scaffolds limit cell infiltration and construct vascularization. To address this problem, we have combined electrospinning with photopatterning to create multiscale porous scaffolds. This process retains the fibrous nature of the scaffolds and permits enhanced cellular infiltration and vascularization when compared to unpatterned scaffolds. This is the first time that photopatterning has been utilized with electrospun scaffolds and is only now possible with the electrospinning of reactive macromers.
image

Keywords:biomaterials  electrospinning  hyaluronic acid  photopatterning  photopolymerization
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号