Structure and stereochemistry of novel ecdysteroids from the roots of Serratula wolffii |
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| Authors: | Mária Takács András Simon Erika Liktor‐Busa Mária Báthori Ferenc Zsila Zsolt Bikádi Péter Horváth Gábor Veress András Gergely Gábor Tóth |
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| Institution: | 1. Department of Pharmaceutical Chemistry, Semmelweis University, H?gyes Endre utca 9, H‐1092 Budapest, Hungary;2. Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szt. Gellért tér 4, H‐1111 Budapest, Hungary;3. Department of Pharmacognosy, University of Szeged, E?tv?s utca 6, H‐6720 Szeged, Hungary;4. Institute of Biomolecular Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Pusztaszeri út 59‐67, H‐1025 Budapest, Hungary;5. Virtua Drug, Ltd., Csalogány utca 4, H‐1015 Budapest, Hungary;6. State Hospital of Cardiology, Balatonfüred, Hungary |
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| Abstract: | Three new natural ecdysteroids viz. 22‐dehydro‐20‐deoxy‐ajugasterone C (1), 1‐hydroxy‐22‐deoxy‐20,21‐didehydro‐ecdysone (2) and 22‐deoxy‐20,21‐didehydro‐ecdysone (3) were isolated from the methanol extract of the roots of Serratula wolffii. The structures of compounds 1–3 were established by various spectroscopic techniques, including one‐ and two‐dimensional NMR, circular dichroism and mass spectroscopic methods. Copyright © 2010 John Wiley & Sons, Ltd. |
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| Keywords: | 1H NMR 13C NMR CD stereo structure ecdysteroids Serratula wolffii |
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