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Structural determination of two new triterpenoids biotransformed from glycyrrhetinic acid by Mucor polymorphosporus
Authors:Xiu Lan Xin  Guowei Yang  Zhan Ping Gou  Ji Hong Yao  Rong Lan  Xiao Chi Ma
Institution:1. Biotechnology Application Center, Beijing Vocational College of Electronic Science and Technology, Beijing, P. R. China;2. School of Pharmacology, Guangdong medical College, Dongguan 523808, P. R. China;3. School of Pharmacy, Dalian Medical University, Dalian 116044, P. R. China
Abstract:Five hydroxylated derivatives of glycyrrhetinic acid by Mucor polymorphosporus were isolated. Among them, 6β, 7β‐dihydroxyglycyrrhentic acid (2) and 27‐hydroxyglycyrrhentic acid (3) are new compounds. Their chemical structures were identified by spectral methods including 2D‐NMR. Copyright © 2009 John Wiley & Sons, Ltd.
Keywords:NMR  1H‐NMR  13C‐NMR  glycyrrhentic acid  biotransformation
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