Stereoselective Synthesis of Ferrocenylamino Acids |
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| Authors: | Maciej Adamczyk Rajarathnam E. Reddy Sushil D. Rege |
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| Affiliation: | Division Organic Chemistry Research (9NM, AP20) , Diagnostics Division, Abbott Laboratories , 100 Abbott Park Road, Abbott Park, IL, 60064-6016 |
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| Abstract: | Enantiopure ferrocenyl-β, and bis-β-amino acids [(R)-(+)-1 and (R, R)-(+)-2] were prepared from (S)-(+)-sulfinimine (3) and (S, S)-(+)-bis-sulfinimine (4) respectively. The desired sulfinimines [(S)-(+)-3 and (S, S)-(+)-4] were prepared from (S)-Andersen reagent (5) and ferrocenecarboxaldehyde (6) and 1, 1 -ferrocenedicarboxaldehyde (7). |
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| Keywords: | 2,3-Dimethyl-2-butenolide 12,13-dimethyl-5,14-dioxabicyclo[9.2.1]-tetradeca-1(13),11-dien-4-one 3,4-dimethylfuran Galerucella macrolide pheromone purple loosestrife Reformatsky |
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