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Stereoselective Synthesis of Allylic Amines by One-Pot Tandem Reaction of Acetylenic Sulfone,Grignard Reagent,and N-Tosylimine |
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| Authors: | Mei-hua Xie Ying Sun Wei Zhang Xiao-xia Gu Xin-yang Zhao Fa-dong Xie |
| Institution: | 1. Anhui Key Laboratory of Functional Molecular Solids, College of Chemistry and Materials Science, Anhui Normal University , Wuhu, Anhui, China xiemh@mail.ahnu.edu.cn;3. Anhui Key Laboratory of Functional Molecular Solids, College of Chemistry and Materials Science, Anhui Normal University , Wuhu, Anhui, China |
| Abstract: | Polysubstituted allylic amines were regio- and stereoselectively synthesized by a one-pot tandem reaction of Cu(I)-catalyzed carbomagnesiation of acetylenic sulfones and its further reaction with N-tosylimine. |
| Keywords: | Acetylenic sulfone allylic amine carbomagnesiation Grignard reagent N-tosylimine |