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Efficient One-Pot Synthesis of Ethyl [2-(2H-Chromene-3yl)-4-oxo-L,3-thiazolidin-3-yl]acetates
Authors:S. Satyanarayana Reddy
Affiliation:Department of Chemistry , Osmania University , Hyderabad, India
Abstract:Ethyl [2-(2H-chromene-3yl)-4-oxo-1,3-thiazolidin-3yl]acetates (6ae) were synthesized in a single pot by the reaction of 2H-3-chromenecarbaldehydes (3ae), glycine ethyl ester hydrochloride (4), and mercaptoacetic acid (5) in diisopropylethylamine/benzene under refluxing conditions in a Dean–Stark trap.
Keywords:2H-3-Chromenecarbaldehydes  Dean–Stark trap  glycine ethyl ester hydrochloride  mercaptoacetic acid  one-pot synthesis
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