Cellulose Sulfuric Acid: Novel and Efficient Biodegradable and Recyclable Acid Catalyst for the Solid-State Synthesis of Thiadiazolo Benzimidazoles |
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| Authors: | B. Suresh Kuarm J. Venu Madhav Y. Thirupathi Reddy P. Narsimha Reddy Peter A. Crooks |
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| Affiliation: | 1. Department of Chemistry , National Institute of Technology , Warangal , AP , India;2. Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky , USA |
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| Abstract: |  An efficient method for the synthesis of 2-substituted benzimidazoles has been developed. In this method, benzo[c][1,2,5]thiadiazole-4,5-diamine was condensed with different aldehydes in the presence of cellulose sulfuric acid under solvent-free conditions by simple physical grinding of reactants using a mortar and pestle at room temperature. The methodology is mild, high-yielding, and green, and the catalyst could be easily recycled. |
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| Keywords: | Benzimidazoles benzo[c][1,2,5]thiadiazole-4,5-diamine cellulose sulfuric acid different aldehydes |
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