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Three-Component Reaction of 5,5-Dimethylcyclohexan-1,3-dione,Aromatic Aldehydes,and Acetonitrile in the Presence of Chlorosulfonic Acid Forming N-[(2-Hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides
Authors:Mohammad Anary-Abbasinejad  Alireza Hassanabadi  Khadijeh Charkhati
Institution:1. Department of Chemistry , Islamic Azad University, Yazd Branch , Yazd, Iran mohammadanary@yahoo.com;3. Department of Chemistry , Islamic Azad University, Yazd Branch , Yazd, Iran
Abstract:A three-component reaction between 5,5-dimethylcyclohexan-1,3-dione (dimedone), aromatic aldehydes, and acetonitrile in the presence of chlorosulfonic acid afforded N-(2-hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides in good yields. The temperature-dependent 1H NMR of one of the products has been investigated.
Keywords:Aromatic aldehydes  chlorosulfonic acid  5  5-dimethylcyclohexan-1  3-dione  multicomponent reaction  temperature-dependent 1H NMR
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