Efficient synthesis and anti-bovine viral diarrhea virus evaluation of 5-(aryldiazo)salicylaldehyde thiosemicarbazone derivatives |
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| Authors: | Samir Y Abbas Khairy A M El-Bayouki Reham M Dawood Tawfeek H Abdelhafez Mostafa K Elawady |
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| Institution: | 1. Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Egypt;2. samiryoussef98@yahoo.com;4. Microbial Biotechnology Department, National Research Centre, Cairo, Egypt |
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| Abstract: | An efficient procedure for the synthesis of 5-(aryldiazo)salicylaldehyde thiosemicarbazone derivatives 1-25 was achieved via the condensation of 5-(aryldiazo)salicylaldehyde derivatives I–V with N-(4)-substituted thiosemicarbazide derivatives. Antiviral activity of the synthesized compounds was carried out. From the obtained results, it was noticed that compound 11 has a strong antiviral activity. |
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| Keywords: | Salicylaldehydes N-(4)-substituted thiosemicarbazides thiosemicarbazones anti-bovine viral diarrhea virus |
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