Facile Synthesis of Triarylpyrimidines with Microwave‐Irradiated Reactions of N‐Phenacylpyridinium Chloride |
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| Authors: | Ping Wu Xi‐Mei Cai Qi‐Fang Wang |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Yangzhou University , Yangzhou, China;2. Yangzhou Polytechnic College , Yangzhou, China;3. College of Chemistry and Chemical Engineering, Yangzhou University , Yangzhou, China |
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| Abstract: | In a system of ammonium acetate and acetic acid under microwave irradiation, N‐phenacylpyridinium chloride 1 reacted with 2 mol of aromatic aldehydes 2a–h to give 2,4,6‐triarylpyrimidine 3a–h, reacted with pyridinecarboxaldehyde 4a–c and acetophenone 5 to yield bipyridine derivatives 6a–c. The structure of the products was characterized with 1H NMR, 13C NMR, IR, and mass spectroscopy. |
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| Keywords: | aldehyde condensation microwave irradiation pyridine pyrimidine |
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