Synthesis of Novel 2-Amino-N-hydroxybenzamide Antimicrobials |
| |
| Authors: | Bellam Mahesh Gundluru Mohan Shaik Ahammed Kabeer Nagam Venkateswarulu Tartte Vijaya |
| |
| Affiliation: | 1. Department of Chemistry, Sri Venkateswara University, Tirupati, India;2. Department of Botany, Sri Venkateswara University, Tirupati, India |
| |
| Abstract: | New 2-amino-N-hydroxybenzamide derivatives (3a–j) have been synthesized in good to excellent yields from the reaction of isatoic anhydride with different hydroxamic acids. All the compounds of the series were screened against both Gram-positive and Gram-negative bacteria and fungi, and some of them have antibacterial and antifungal activities compared to the standard drugs. |
| |
| Keywords: | Antimicrobial agents benzamide hydroxamic acid isatoic anhydride |
|
|
