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Bis(O-nitrophenyl) Carbonate as a New Reagent for the Synthesis of Chiral Oxazolidin-2-ones |
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| Authors: | Monika Simon Andreea Micle Valentin Badea Carol Csunderlik |
| Institution: | 1. Department of Applied Chemistry and Organic and Natural Compound Engineering , Politehnica University of Timisoara, Industrial Chemistry and Environmental Engineering Faculty , Timisoara, Romania monika.simon@chim.upt.ro;4. akinomis@yahoo.com;5. Department of Applied Chemistry and Organic and Natural Compound Engineering , Politehnica University of Timisoara, Industrial Chemistry and Environmental Engineering Faculty , Timisoara, Romania |
| Abstract: | Bis(o-nitrophenyl) carbonate reacts under mild conditions with chirals 1,2-amino alcohols and, after addition of DMAP, affords the corresponding oxazolidin-2-ones in very good yields. |
| Keywords: | Bis(o-nitrophenyl) carbonate (4R 5S)-4 5-diphenyl-2-oxazolidinone (4S)-4-isopropyl-2-oxazolidinone (S)-4-(phenylmethyl)-2-oxazolidinone |