Practical Synthesis of 4-Benzylidene-2-phenyl-5(4H)-oxazolones |
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| Authors: | V Siddaiah G Mahaboob Basha D Sudhakar R Srinuvasarao Y Santosh Kumar |
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| Institution: | 1. Department of Organic Chemistry and Foods, Drugs and Water Analysis , Andhra University , Visakhapatnam , India siddaiah_v@yahoo.com;3. Department of Organic Chemistry and Foods, Drugs and Water Analysis , Andhra University , Visakhapatnam , India |
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| Abstract: | A simple and alternative method has been developed for the synthesis of 4-benzylidene-2-phenyl-5(4H)-oxazolones via reactions of hippuric acid with various aldehydes in the presence of 2-chloro-4,6-dimethoxy-1,3,5-triazine/N-methylmorpholine at 75 °C. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file. |
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| Keywords: | 4-Benzylidene-2-phenyl-5(4H)-oxazolone CDMT cynuric chloride hippuric acid NMM |
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