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Phosphomolybdic Acid/SiO2 as Heterogeneous Solid Acid Catalyst for the Rapid Synthesis of N-Substituted Pyrroles
Authors:M. Anil Kumar  A. Bala Krishna  B. Hari Babu  C. Bhupendra Reddy
Affiliation:Department of Chemistry , Sri Venkateswara University , Tirupati, India
Abstract:Isatins react efficiently with 4-hydroxyproline in the presence of 10 mol% of PMA/SiO2 in acetonitrile/water (4:1) under reflux conditions to furnish N-substituted pyrroles in excellent yields. Similarly, 11H-indeno[1,2-b]quinoxalin-11-ones also participated in this reaction.
Keywords:Heteropoly acid  4-hydroxy proline  isatins  pyrroles
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