1. Department of Chemistry , Zhejiang University , Hangzhou, China leiming@zju.edu.cn;3. Department of Chemistry , Zhejiang University , Hangzhou, China;4. Zhejiang Hisun Pharmaceutical Co. , Taizhou, China
Abstract:
Polymer-supported 4-aminoformoyldiphenylammonium triflate (PS-AFDPAT) was used as an effective catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Biginelli reaction. This immobilized catalyst could be easily recovered by simple filtration and recycled for 10 runs without significant decrease of the catalytic activity.