DBU-CH3I,a Potential Substitute for CH2N2 in the Preparation of Methyl Esters and Methyl Aryl Ethers: Studies with Assorted Acids |
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| Authors: | Dipakranjan Mal Amit Jana Sutapa Ray Sourav Bhattacharya Asit Patra Saroj R De |
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| Institution: | 1. Department of Chemistry , Indian Institute of Technology , Kharagpur , India dmal@chem.iitkgp.ernet.in;3. Department of Chemistry , Indian Institute of Technology , Kharagpur , India |
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| Abstract: | DBU-CH3I has been poised to be a substitute for diazomethane in the preparation of methyl esters from carboxylic acids. The reactions can be carried out in commercial untreated acetone and acetonitrile, which have been exemplified with several methyl esters, otherwise it is difficult to prepare. Bis-esterification using diiodomethane can also be achieved in a similar fashion. Sufficiently acidic phenols are also conveniently O-methylated by the method. |
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| Keywords: | DBU diiodomethane iodomethane phenols phthalaldehydic acids pyridine carboxylic acids |
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