Short and Efficient Synthesis of Rubrolide E |
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| Authors: | Subhash P Chavan Ashok B Pathak Ankur Pandey Uttam R Kalkote |
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| Institution: | 1. Division of Organic Chemistry: Technology , National Chemical Laboratory , Pune, 411008, India sp.chavan@ncl.res.in;3. Division of Organic Chemistry: Technology , National Chemical Laboratory , Pune, 411008, India |
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| Abstract: | Short and efficient synthesis of rubrolide E from commercially available 4‐methoxyacetophenone, employing ring‐closing metathesis, Knoevenagel condensation, and Reformatsky reactions, are the key steps are described. |
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| Keywords: | antibiotics antitumor epoxide natural products total synthesis |
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