Atom-Economic Route to Densely Functionalized Thiophenes via Base-Catalyzed Rearrangement of 5-Propargyl-2H-thiopyran-4(3H)-ones |
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| Authors: | Chunlin Tang Jian Qin |
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| Institution: | 1. Department of Chemistry, Northeast Normal University, Changchun, China;2. Department of Chemistry and Environmental Science, Jinzhou Teachers Training College, Jinzhou, China |
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| Abstract: | An atom-economic route to densely functionalized thiophenes has been developed via base-catalyzed rearrangement of 5-propargyl-2H-thiopyran-4(3H)-ones involving tandem retro-thio Michael addition, propargyl isomerization, and intramolecular thio-addition to allenes. |
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| Keywords: | DBU gem-dialkylthio enynes 5-propargyl-2H-thiopyran-4(3H)-ones rearrangement thiophenes |
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