Facile One-Pot Synthesis of Aryl,Heteryl Substituted Hydrazono Thiazolyl-Pyrazolone Derivatives via Three-Component Reaction |
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| Authors: | Venkata Sreenivasa Rao Chunduru |
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| Affiliation: | Department of Chemistry , National Institute of Technology , Warangal , India |
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| Abstract: | A facile, one-pot, three-component bis heterocyclized reaction for the synthesis of hydrazonothiazolyl-pyrazolones has been described. Reaction of phenacyl bromides or 3-(2-bromoacetyl)coumarins, with thiosemicarbazide and ethyl 2-(2-arylhydrazono)-3-oxobutanoates in AcOH/NaOAc, gave the corresponding products in good yields. All the synthesized compounds were characterized by their analytical and spectral data. |
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| Keywords: | 3-(2-Bromoacetyl)coumarin one-pot synthesis phenacyl bromide thiazolyl-pyrazolone thiosemicarbazide |
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