Facile One-Pot Method for the Synthesis of Novel N-Dichloroacetyl-1,3-oxazolidines |
| |
| Authors: | Ying Fu Fei Ye Jingdong Mao Xiaotian Wen |
| |
| Affiliation: | 1. Department of Applied Chemistry , Harbin Institute of Technology , Harbin, Heilongjiang, China;2. College of Science, Northeast Agricultural University , Harbin, Heilongjiang, China;3. College of Science, Northeast Agricultural University , Harbin, Heilongjiang, China;4. Department of Chemistry and Biochemistry , Old Dominion University , Norfolk, Virginia, USA |
| |
| Abstract: | A short and efficient route to synthesis and structural characterization of a series of novel N-dichloroacetyl-5-ethyl-1,3-oxazolidine derivatives has been developed. These new compounds, characterized by the substitution at position 2 by alkyls, cycloalkanes, benzyls, or aryls, have been synthesized in good yields via a sequential procedure involving cycloaddition, condensation, and acylation. All the compounds are characterized by infrared, 1H NMR, and 13C NMR. |
| |
| Keywords: | Acylation condensation cycloaddition dichloroacetyl oxazolidines synthesis |
|
|
