Novel Synthesis of N‐Methyl Spiropyrrolidines by 1,3‐Dipolar Cycloaddition Reaction of Azomethine Ylides |
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| Authors: | G Subramaniyan J Jayashankaran |
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| Institution: | Department of Organic Chemistry , University of Madras , Chennai, India |
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| Abstract: | A series of novel N‐methyl spiropyrrolidines have been synthesized in good yield by the cycloaddition reaction of azomethine ylides generated by a decarboxylative route from sarcosine and paraformaldehyde with conformationally locked s‐trans enone functionality present in the (E)‐3‐arylidene‐4‐chromanone as dipolarophiles. The structure of the title compound was established by spectroscopic techniques. |
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| Keywords: | 1 3‐dipole azomethine ylide spiropyrrolidines |
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