Copper-Catalyzed Synthesis of Valuable Heterocyclic Compounds Using a Tandem Oxidation Process Approach |
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| Authors: | Vineet Jeena Siphamandla Sithebe Ross S Robinson |
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| Institution: | 1. School of Chemistry and Physics, University of KwaZulu-Natal, Scottsville, Pietermaritzburg, South AfricaJeenav1@ukzn.ac.za;3. School of Chemistry and Physics, University of KwaZulu-Natal, Scottsville, Pietermaritzburg, South Africa |
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| Abstract: | The synthesis of quinoxalines via a tandem oxidation process using a copper acetate monohydrate/2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) oxidative system has been described. Using this approach, a series of quinoxaline derivatives were formed in good yields within short reaction times under microwave irradiation. The oxidative system was also extended to the selective synthesis of dihydropyrazines and pyrazines. |
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| Keywords: | Copper microwave quinoxalines tandem oxidation process |
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