Efficient One-Pot Synthesis of 2-Chloro-1,1, 1-trifluoro-2-alkenes Under Solvent-Free Conditions |
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| Authors: | Mu-Wang Chen Ping Zhong Mao-Lin Hu |
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| Institution: | College of Chemistry and Materials Engineering, Wenzhou University , Wenzhou, Zhejiang, China |
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| Abstract: | The improved one-pot Wittig reaction had been used to prepare trifluoromethyl-containing olefins under solvent-free conditions. Treatment of aldehydes with PPh3 and CF3CCl3 in the presence of K2CO3 at 100 °C afforded 2-chloro-1,1,1-trifluoro-2-alkenes in good to moderate yields. |
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| Keywords: | Olefins one pot solvent free trifluoromethyl Wittig reaction |
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