|
|||||
|
|
Convenient Method for the 3‐Functionalization of Isoindazoles |
|
| Authors: | Aaron Bunnell Counde O'Yang Andra Petrica |
| Institution: | Department of Medicinal Chemistry , Roche Palo Alto LLC , Palo Alto, California, USA |
| Abstract: | The C‐3 position of isoindazoles is readily functionalized by metalation with lithium diisopropylamide followed by reaction with a variety of electrophiles. |
| Keywords: | Deprotonation functionalization 2H‐indazoles isoindazoles |