New Route for Conversion of Camptothecin to 7‐Ethylcamptothecin and 7‐Propylcamptothecin |
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| Authors: | Xin Wang Ning Cheng Huiqing Zhao Zhihong Gu Xiang Shen |
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| Affiliation: | 1. Department of Chemistry , College of Basic Medicine, Anhui Medical University , Hefei, Anhui, China;2. School of Chemical Engineering, Hefei University of Technology , Hefei, Anhui, China;3. First Affiliated Hospital, Anhui Medical University , Hefei, Anhui, China |
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| Abstract: | In this article, a new route for conversion of camptothecin to 7‐ethylcamptothecin and 7‐propylcamptothecin is described. Compared with previous reports, the reaction time of the new synthetic route was greatly shortened to 30 min, and the products were obtained in high yield. |
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| Keywords: | camptothecin 7‐ethylcamptothecin high yield new route 7‐propylcamptothecin |
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