Reaction of Anthranilonitrile with Some Active Methylene Reagents: Synthesis of Some New Quinoline and Quinazoline Derivatives |
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| Authors: | Nadia H. Metwally |
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| Affiliation: | Chemistry Department , Faculty of Science, Cairo University , Giza, Egypt |
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| Abstract: | Anthranilonitrile (1) reacts with ethyl cyanoacetate and its dimer, malononitrile, cyanothioacetamide and N‐arylidene cyanoacetohydrazides 12a–c to afford pyrano[2,3‐b]quinoline 5, cyanomethyl‐quinazoline 10, pyrazolo[2,3‐a]quinazoline 12 and triazolo[4,3‐a]‐quinoline derivatives 16a–c, respectively. Structures and conceivable mechanisms are discussed. |
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| Keywords: | Anthranilonitrile cyanacetohydrazide quinazoline quinoline |
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