Solvent‐Free Passerini Reactions |
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Authors: | Dominik Koszelewski Wiktor Szymanski Joanna Krysiak |
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Institution: | Institute of Organic Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, 01‐224, Warsaw, Poland |
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Abstract: | The influence of the substrate structure and concentration on the yield of the Passerini reaction was studied. A new, solvent‐free methodology for a convenient preparation of α‐acyloxyamides 4 was established and compared to the classical methodology. A higher reaction yield was obtained in shorter time, especially in the case of aromatic aldehydes. |
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Keywords: | α‐acyloxyamides aromatic aldehydes Passerini reaction solvent free |
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