Atom-Efficient,Solvent-Free,Green Synthesis of Chalcones by Grinding |
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| Authors: | Nora M Rateb |
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| Institution: | Department of Chemistry , Faculty of Science, Cairo University , Giza, Egypt |
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| Abstract: | An improved Claisen–Schmidt condensation reaction of methyl ketones and aromatic aldehydes can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions. |
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| Keywords: | Chalcones Claisen–Schmidt condensation green chemistry grinding solvent-free synthesis |
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