DIC-Mediated Coupling of Carboxylic Acids to (4R, 5S)-4-Methyl-5-Phenyl-2-Oxazolidinone |
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| Authors: | James M. Graham Brock T. Shireman Todd M. Maddux Christina M. Brandstedt Wayne E. Zeller |
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| Affiliation: | 1. Department of Chemistry , Knox College , Galesburg, Illinois, 61401;2. Department of Chemistry , Illinois State University , Normal, Illinois, 61790-4160 |
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| Abstract: | The use of diisopropylcarbodiimide as an agent to effect the coupling of carboxylic acids to Evans' chiral auxiliary (4R, 5S)-4-methyl-5-phenyl-2-oxazolidinone provides the corresponding acyl derivatives in good yields. |
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